Content Notices
Piperacillin-Tazobactam Dosing Correction - 2/21/11
The Sanford Guide to Antimicrobial Therapy 2010 edition
Table 17A, Renal Impairment Dose Adjustments
Pip-Tazo dose for CRRT (Continuous Renal Replacement Therapy)
The dose should be 2.25 gm q6h
Please note the correction in your book.
GAT 2010: Antibiotics Before Dental Procedure - 5/13/10
Affects: All editions
Nature: Clarification
Page: 177
Under Orthopedic surgery, last entry in the left column, the referenced study (CID 50:8, 2010) concluded that antibiotic prophylaxis prior to dental procedures did not decrease the risk of subsequent total hip or knee infection.
GAT 2009: Table 17A: Oseltamavir Dosing - 10/3/09
Affects: All editions
Nature: Correction
Page: 186
Oseltamivir dose for CrCl< 30mL/min should correctly read 75 mg once daily
GAT 2009: Metronidazole Renal dose - 7/22/09
Affects: All editions
Nature: Updated information
Page: 181
Renal dose adjustments for metronidazole should be updated as follows:
• CrCl >50: Usual dose
• CrCl 10-50: Usual dose
• CrCl <10: 50% of usual dose q12h
• HEMO: Usual dose + 50% of normal dose as supplement after dialysis
• CAPD: 50% of usual dose q12h
• CRRT: Usual dose
• End stage liver disease: 50% of usual dose q12h
GAT 2009: Aspergillosis, table 11A - 7/20/09
Affects: All editions
Nature: Correction
Page: 97
For invasive, pulmonary or extrapulmonary aspergillosis, the voriconazole dose should read:
Voriconazole 6 mg/kg IV q12h on day 1, then either 4 mg/kg IV q12h or ...
GAT 2009: Pocket Edition - 4/29/09
Affects: Some copies of the pocket edition
Nature: Text obscured
Page: 39
A printing anomaly may obsure part of the suggested regimens for Legionella sp., Hospitalized/Immunocompromised. Moxi IV is obscurred.
The regimen should read: Azithro IV or Levo IV or Moxi IV (See Table 10C, pages 91 & 93 for dosages). Treat for 7-14 days (CID 39:1734, 2004)

